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n-Propyl bromide

This fact sheet is part of a series of chemical fact sheets developed by TURI to help Massachusetts companies, community organizations and residents understand the chemical's use and health and environmental effects, as well as the availability of safer alternatives. 

N-Propyl bromide (nPB) or 1-bromopropane, is a relatively new solvent that is used in vapor degreasing, metal cleaning, and dry cleaning; as a solvent carrier in adhesives; and as a chemical intermediate. The US Environmental Protection Agency (EPA) classifies nPB as a volatile organic compound (VOC).

Use of nPB is increasing as an alternative for other solvents that have become more strictly regulated, such as methylene chloride, perchloroethylene (perc), and trichloroethylene (TCE). This trend is of concern because evidence has emerged linking nPB to a range of human health hazards. 

nPB has been reportable under the Toxics Use Reduction Act (TURA) since 2010. Effective January 2016, nPB is designated as a Higher Hazard Substance under TURA. Under this designation, Massachusetts facilities in TURA-covered sectors with ten or more employees are subject to reporting, planning and fee requirements if they use 1,000 pounds or more of nPB annually.

For more information, download the fact sheet.