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Massachusetts Chemical Fact Sheets

Massachusetts Chemical Fact Sheets describe the hazards, exposure routes, uses and alternatives, and regulatory context for selected chemicals, including those on the Toxics Use Reduction Science Advisory Board's list of 'more hazardous chemicals.'

Toluene Diisocyanates

  Toluene-2,6-diisocyanate (2,6-TDI), toluene-2,4-diisocyanate (2,4-TDI), and toluene diisocyanate mixed isomers are the three forms of TDI commonly used in commerce. Acute exposure to TDIs can result in severe skin, eye, lung, and throat irritation. TDIs are possible carcinogens and may be teratogens (reproductive hazards). Workplaces are the primary source of exposure to TDIs, which are intermediary chemicals in the manufacture of polyurethanes. In Massachusetts, businesses used 7.4 million pounds of TDIs in 1998. Download PDF file (137.03 kB)

Trichloroethylene (TCE)

  Trichloroethylene is a man-made solvent. One of this solvents major uses is a cleaning agent. TCE has been listed by the EPA as a probable human carcinogen and a possible reproductive hazard (teratogen). Acute exposure to TCE affects the central nervous system, the kidneys and the liver. Because of its potential health effects, this chemical is regulated throughout its lifecycle. Many uses are heavily restricted due to its toxicity. Download PDF file (94.17 kB)

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