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n-Propyl Bromide (nPB)

N-Propyl bromide (nPB) or 1-bromopropane, is a solvent that is used in vapor degreasing, metal cleaning, and dry cleaning; as a solvent carrier in adhesives; and as a chemical intermediate. The US Environmental Protection Agency (EPA) classifies nPB as a volatile organic compound (VOC).

Use of nPB is increasing as an alternative for other solvents that have become more strictly regulated, such as methylene chloride, perchloroethylene (perc), and trichloroethylene (TCE). This trend is of concern because evidence has emerged linking nPB to a range of human health hazards. In 2009, nPB was added to the list of Toxic or Hazardous Substances subject to regulations under the Massachusetts Toxics Use Reduction Act (TURA).

N-Propyl bromide is designated as a Higher Hazard Substance under TURA, which lowers the reporting threshold to 1,000 lb/year, effective January 2016.

Information about N-Propyl bromide prepared by the TURA Program

Content Category Publication Type Title Year Description
Overview Fact Sheet n-Propyl Bromide Fact Sheet 2014 TURI Chemical Fact Sheets describe the hazards, exposure routes, uses and alternatives, and regulatory context for selected chemicals.
Policy Policy Analysis n-Propyl Bromide Policy Analysis 2014 TURA Policy Analyses are developed as background for state-level decision-making about individual chemicals, chemical classes, and industry sectors.


Information from other resources


Source Title Year Description
NIOSH Field Study 2015 Workers' exposures to n-propyl bromide at a printed electronics circuit assembly manufacturer.
NIOSH Hazard Alert 2013 General information on nPB exposures, health effects, and help resources.
NIOSH Field Study 2007 Workers' exposures to n-propyl bromide at an aerospace components manufacturer.
NIOSH Field Study 2007 Workers' exposures to n-propyl bromide at an optical prism and optical assemblies manufacturer.
California Hazard Evaluation System and Information service  Early Warning and Prevention: 1_Bromopropane (1-BP) 2017 New evidence says it causes cancer.