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Life Sciences

Averica Discovery Services Inc. - Supercritical Fluid Chromatograhy. OTA 2015

  Averica Discovery Services is a specialty contract research organization in Marlborough, Massachusetts. The biotech and life sciences industries rely on the services of CROs like Averica to support their work to develop potential new drugs. Compound supply and proper analytic services are critical to a fast-moving, chemistry-driven research and development program. Averica’s services enable mechanistic studies, early stability assessment, analytical development and purification for small molecule drug study applications with the U.S. Food and Drug Administration (FDA). Download PDF file (274.17 kB)

ChemGenes Corporation - Solvent Recovery and Recycling. 2013.

  ChemGenes has a long history with Toxics Use Reduction (TUR). Working with the Office of Technical Assistance (OTA) since 2005, the company has reduced its use of chloroform by 55 percent and hexane by 35 percent, resulting in a net savings of $215,000. Then, in 2012, the Toxics Use Reduction Institute (TURI) at UMass Lowell awarded ChemGenes an incentive grant to help offset capital costs for a new solvent recovery and recycling system. The facility collected data, presented in this case study, from May through August 2013 of each batch run with the new system. In the long-term, ChemGenes expects to reduce the use of hexane and ethyl acetate by 27,000 pounds or 70 percent annually. Factoring in the TURI grant, ChemGenes estimates a return on investment in less than two years. Download PDF file (3.46 MB)